Nickel allergy nitinol stent
Some may also contain cobalt, molybdenum, or other metals. Methods We examined nickel release from seven commonly used intracranial stents: Enterprise, LVIS Jr, Neuroform, Wingspan, Zilver, Pipeline Flex Embolization Device, and Surpass Evolve. Evidence shows that many people first become allergic to nickel from body piercing. Some stents are made of nitinol which is a mixture of titanium and nickel. Many coronary stents are made from stainless steel, which is steel with added nickel and chromium, and nickel is one of the most common causes of allergic contact dermatitis (ACD).
First, will a substance that causes an allergic reaction on the skin, also cause a problem when implanted inside of an artery or vein? There are strict bans in Europe on the use of nickel on objects that touch or pierce the skin and hence there is a much lower prevalence of nickel allergy in Europe. Nickel is a major component of the cobalt alloy used in aneurysm clips and also of nitinol, which is commonly used in flow diverters and intracranial stents.
Although nickel allergy is a common cause of contact dermatitis, systemic reactions to nitinol stents are rare.
All stents used in arteries or veins have some component of nickel in them. However, there are thousands of other less common substances in our environment that have the potential to cause allergic contact rashes in certain individuals. Medical stents are mostly made of metal and are commonly used to maintain blood flow to the legs, heart, brain, and other organs. Second, what type of adverse reaction could occur if someone was allergic to the metal in the stent?
Angiography revealed an external iliac artery stenosis, which was treated with a nitinol stent graft. This is known as rhus dermatitis and is easily recognizable by most licensed physicians. A variety of metals are used including stainless steel which often contains nickel, chrome, cobalt and other metals.
Help! I need a stent and I’m allergic to nickel!
A year-old woman had presented with a nonhealing toe wound. The two main concerns are that if a person is allergic to the metal it may lead to . As stenting has increased worldwide, many patients and physicians have questioned the safety of stents in those with nickel allergies. The first use of a stent was in the coronary artery in Since that time, stenting has become commonplace for a variety of medical conditions.
Some may also contain cobalt, molybdenum, or other metals.
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. Many coronary stents are made from stainless steel, which is steel with added nickel and chromium, and nickel is one of the most common causes of allergic contact dermatitis (ACD). For example, a poorly constructed low quality metal belt buckle may easily release nickel on the skin and cause a rash in a nickel allergic patient. There is a direct correlation in the US between the number of body piercings a person has and the rate of allergy to nickel.
The gold standard to diagnose allergic contact dermatitis is through a painless and noninvasive office test known as epicutaneous patch testing which is performed on the skin by dermatologists and some allergists. It is not the mere presence of nickel that causes an allergy; rather it is the ability of a metal to release nickel on to the skin that causes an allergy.
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Our literature review identified 9 articles reporting 10 unique cases of nickel-related adverse events after aneurysm treatment. For this reason, testing is not needed to prove the diagnosis. Nickel is one of the most common causes of allergic contact dermatitis — a skin rash or irritation caused by touching a particular substance.
Some stents are made of nitinol which is a mixture of titanium and nickel. Thus, a possible association between metal hypersensitivity and stent restenosis has been questioned.
Nickels and tines: the myth of nickel allergy in intracranial stents - Journal of NeuroInterventional Surgery
We incubated each stent in human plasma-like media for 30 days. The most common allergen a substance that causes an allergic reaction found on patch testing in the United States is nickel. Although nickel allergy is a common cause of contact dermatitis, systemic reactions to nitinol stents are rare.
On the other hand, high grade stainless steel would not release enough nickel to cause a rash because the nickel is so tightly bound within the steel. Neurological injury following endovascular treatment with a nickel containing intracranial stent has been reported in patients with purported nickel allergy, but it is unclear . A year-old woman had presented .